PROSPER Evidence
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— Published Research Related to Positive Youth Outcomes —
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Preventing substance misuse through community-university partnerships: Randomized controlled trial outcomes 4½ years past baseline.
Spoth, R., Redmond, C., Clair, S., Shin, C., Greenberg, M., & Feinberg, M.
(2011).
Preventing substance misuse through community-university partnerships: Randomized controlled trial outcomes 4½ years past baseline.
American Journal of Preventive Medicine, 40(4), 440-447.
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Background: Substance misuse by adolescents and related health issues constitute a major public
health problem. Community-based partnership models designed for sustained, quality implementation
of proven preventive interventions have been recommended to address this problem. There is
very limited longitudinal study of such models.
Purpose: To examine the long-term fındings from an RCT of a community–university partnership
model designed to prevent substance misuse and related problems.
Design/setting/participants: A cohort sequential design included 28 public school districts in
rural towns and small cities in Iowa and Pennsylvania that were randomly assigned to community–
university partnership or usual-programming conditions. At baseline, 11,960 students participated,
across two consecutive cohorts. Data were collected from 2002 to 2008.
Intervention: Partnerships supported community teams that implemented universal, evidencebased
interventions selected from a menu. The selected family-focused intervention was implemented
with 6th-grade students and their families; school-based interventions were implemented
during the 7th grade. Observations demonstrated intervention implementation fıdelity.
Main outcome measures: Outcome measures were lifetime, past-month, and past-year use of a
range of substances, as well as indices of gateway and illicit substance use; they were administered at
baseline and follow-ups, extending to 4.5 years later.
Results: Intent-to-treat, multilevel ANCOVAs of point-in-time use at 4.5 years past baseline were
conducted, with supplemental analyses of growth in use. Data were analyzed in 2009. Results showed
signifıcantly lower substance use in the intervention group for 12 of 15 point-in-time outcomes, with
relative reductions of up to 51.8%. Growth trajectory analyses showed signifıcantly slower growth in
the intervention group for 14 of 15 outcomes.
Conclusions: Partnership-based implementation of brief universal interventions has potential for public
health impact by reducing growth in substance use among youth; a multistate network of partnerships
is being developed. Notably, the tested model is suitable for other types of preventive interventions.
(Am J Prev Med 2011;40(4):440–447) © 2011 American Journal of Preventive Medicine
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Substance use outcomes at 18 months past baseline from the PROSPER community-university partnership trial.
Spoth, R., Redmond, C., Shin, C., Greenberg, M., Clair, S., & Feinberg, M.
(2007).
Substance use outcomes at 18 months past baseline from the PROSPER community-university partnership trial.
American Journal of Preventive Medicine, 32(5), 395-402.
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