PROSPER has been recognized by leading prevention science organizations and the 4-H Council.

The Coalition for Evidence-Based Policy has selected PROSPER as a Near Top-Tier Program. Interventions shown to meet almost all elements of the Top Tier standard, and which only need one additional step to qualify. This category includes, for example, interventions that meet all elements of the standard in a single site, and just need a replication trial to confirm the initial findings and establish that they generalize to other sites.

Blueprints for Healthy Youth Development has designated PROSPER as a Promising Program. Each Blueprints program has been reviewed by an independent panel of evaluation experts and determined to meet a clear set of scientific standards. Programs meeting this standard have demonstrated at least some effectiveness for changing targeted behavior and developmental outcomes.

The Social Impact Exchange has selected PROSPER for its index of top nonprofits increasing social impact, the S&I 100. The S&I 100 Index consists of high-impact nonprofits that have been carefully vetted through a comprehensive selection process. More than 150 experts have participated in a cross-sector collaborative effort to identify and assess the nonprofits that have been selected to be part of the Index. ​

PROSPER was selected for the 2007 Family Strengthening Award that was given jointly by the National 4-H Council and the Annie E. Casey Foundation. The PROSPER Project also was selected by the National 4-H Council as a Program of Distinction in 2006 and in 2009.

The Evidence-Based Programs on the PROSPER menu also have received numerous recognitions.

For example, the Strengthening Families Program: For Parents and Youth 10-14 has been recognized by SAMHSA, the Office of Juvenile Justice and Delinquency, CSAP, and the 4-H Council.